News
Spinogenix's Fragile X Syndrome drug shows normalisation of brain function
7+ hour, 4+ min ago (476+ words) In the Phase IIa study, 10 adult male patients with FXS received one oral dose of SPG601. Spinogenix's Fragile X Syndrome (FXS) drug is the first to show rescued well-established resting EEG abnormalities, suggesting a normalisation of brain function. The Phase IIa…...
Idorsia reports positive data for paediatric insomnia study of daridorexant
1+ week, 2+ day ago (315+ words) Idorsia has reported positive top-line data from its Phase II dose-finding trial evaluating daridorexant, a dual orexin receptor antagonist, for paediatric insomnia disorder. The randomised study assessed 10mg, 25mg, and 50mg doses in children aged 10 to under 18 with insomnia, to characterise the dose-response…...
Oral vaccine cuts up to 80. 6% of E. coli-triggered diarrhoea cases
2+ week, 10+ hour ago (474+ words) The ETEC vaccine will now enter a pivotal Phase III trial across different countries and populations. A novel oral vaccine, ETVAX, has demonstrated its potential to reduce paediatric cases of moderate-to-severe enterotoxigenic E. coli (ETEC)-triggered diarrhoea by up to 80. 6% in…...
Study explores links between gestational diabetes, prenatal depression and childhood obesity
1+ mon, 2+ hour ago (519+ words) In the February 2026 edition of JAMA Network Open, a study explored the impact of two health indicators, gestational diabetes and maternal prenatal depression, on childhood obesity. In the US, the burden of childhood obesity has posed a formidable public health…...
Dia Medica gains Health Canada approval for Phase II preeclampsia trial
1+ mon, 3+ day ago (307+ words) Recruitment is expected to begin later this year, with plans for geographic expansion into the UK and the US. Dia Medica Therapeutics has received Health Canada clearance for its clinical trial application to begin a Phase II study assessing DM199 in…...
Lilly and Incyte to seek approval of alopecia JAK inhibitor in children
5+ mon, 2+ week ago (374+ words) Lilly and Inctye will be seeking a label update for the JAK inhibitor for its use in paediatric patients. Eli Lilly and Incyte's oral JAK inhibitor has shown benefit in hair regrowth in paediatric patients with severe alopecia areata. Among…...
RSV threat in premature babies could be minimised with immunisation coverage
8+ mon, 2+ week ago (499+ words) Each year in the UK, 30, 000 children under the age of five are hospitalised with RSV and it causes around 30 infant deaths. Seasonal epidemics of respiratory syncytial virus (RSV) have a significant health burden in children in the UK. RSV is…...
Study explores link between maternal asthma and ASD development in children
8+ mon, 4+ week ago (410+ words) According to the World Health Organization, autism spectrum disorder (ASD) affects approximately 10% of children globally. ASD is theorised to be caused by a combination of genetic and environmental factors, including maternal asthma. Maternal asthma, defined as asthma existing in mothers…...
WHO warns that polio cases are on the rise
11+ mon, 3+ week ago (353+ words) The World Health Organization (WHO) has released an update on polio following the March 2025 meeting of the International Health Regulations Emergency Committee. Polio, which can cause lifelong disability, has been eradicated in Europe, the Americas, much of the western Pacific,…...