4+ hour, 13+ min ago  (98+ words) 1. High-fidelity adherence to an enhanced recovery protocol was associated with a significantly shorter length of stay and fewer complications compared to low-fidelity care in pediatric patients undergoing elective gastrointestinal surgery. 2. Protocol adherence improved across study phases, and electronic health record…...

1+ mon, 1+ week ago  (348+ words) 2 Minute Medicine 1. Adopted individuals who experienced improved environmental conditions had better long-term psychosocial outcomes than their unadopted biological siblings, with some advantages also observed in the next generation. Evidence Rating Level: 2 (Good) Improving home environments during early life can benefit…...

2+ mon, 1+ week ago  (111+ words) 1. In this phase 1/2a trial involving patients with Dravet syndrome who received intrathecal zorevunersen, treatment-related adverse events occurred in nearly half of patients but were generally mild to moderate in severity. 2. Zorevunersen was associated with reduced seizure frequency and improvements in…...

2+ mon, 1+ week ago  (635+ words) 2 Minute Medicine 1. In this cohort of singleton offspring, placental abruption during pregnancy was associated with significantly increased risk of cardiovascular mortality and nonfatal cardiovascular events from infancy onward. Evidence Rating Level: 2 (Good) Cardiovascular disease (CVD) remains the leading global cause of…...

2+ mon, 1+ week ago  (369+ words) 2 Minute Medicine 1. In this randomized controlled trial, bottom'vented bottles did not reduce mild gastrointestinal discomfort overall in infants aged 090 days. Evidence Rating Level: 1 (Excellent) Bottle feeding infants in the first 6 months has become more common, with over 60% reported, which may…...

2+ mon, 3+ week ago  (329+ words) 2 Minute Medicine 1. High-frequency oscillatory ventilation (HFOV) may reduce the incidence of bronchopulmonary dysplasia (BPD) compared with conventional mechanical ventilation (CMV) in infants born at 34 weeks" gestation or earlier with neonatal respiratory distress syndrome (NARDS). Evidence Rating Level: 1 (Excellent) NARDS is a…...

3+ mon, 5+ day ago  (361+ words) 2 Minute Medicine 1. In this cohort of very preterm infants, maternal exposure to low levels of greenness, high levels of ozone, and low temperatures was associated with decreased odds of infant survival without major morbidity (SWMM). Evidence Rating Level: 2 (Good) Exposure…...

3+ mon, 1+ week ago  (297+ words) 2 Minute Medicine 1. Adults with attention-deficit/hyperactivity disorder are more likely to discontinue antihypertensive therapy and demonstrate poor long-term adherence. 2. Use of attention-deficit/hyperactivity disorder medication is associated with improved adherence to antihypertensive treatment among affected individuals Evidence Rating Level: 2 (Good)…...

3+ mon, 2+ week ago  (315+ words) 2 Minute Medicine 1. Prenatal depression and gestational diabetes were independently associated with a higher risk of childhood obesity within the first 10 years of life, with gestational diabetes showing a greater risk. 2. Children exposed to both conditions had the highest risk of…...

4+ mon, 1+ week ago  (627+ words) 2 Minute Medicine 1. In this retrospective cohort study, both low and high early-pregnancy hemoglobin levels were linked to higher rates of severe neonatal morbidity and mortality (SNM-M), stillbirth, and preterm birth before 37 weeks. 2. High hemoglobin, but not low hemoglobin, was associated…...